Just like with targeted therapy, if you’re able to identify proteins unique to the cancer cells (or only found on a few other normal cells), side effects are reduced. Additionally, because the chemotherapy is only being applied to certain cells, a higher “dose” of the chemotherapy medication can be delivered, making it more effective at killing the cancer. Right drug, in the right place, at the right time!
- Okeley NM, Miyamoto JB, Zhang X, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research. 2010;16(3):888-897. doi:10.1158/1078-0432.ccr-09-2069.