The cancer cells get their magic from specific proteinsPRO-TEEN — A naturally occurring, large, complex substance made up of amino acids that is an essential part of living organisms. When one of the magic proteins (key) interlocks with a particular protein on an immune cell (lock), the cancer cell sends a signal to the immune cell, telling it to stop. When the key fits into the lock, the immune cells won’t respond. The immune cells are locked out and unable to find (and destroy) the cancer.
- La-Beck NM, Jean GW, Huynh C, Alzghari SK, Lowe DB. Immune Checkpoint Inhibitors: New Insights and Current Place in Cancer Therapy. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2015;35(10):963-976.